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Human neutrophil α-defensin HNP1 interacts with bacterial cell wall components to promote biofilm formation by Staphylococcus aureus

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Staphylococcus aureus is a major opportunistic pathogen whose ability to form biofilms significantly enhances its persistence and antibiotic resistance. We previously found that human neutrophil peptide 1 (HNP1), a member of the α-defensin family, promotes bi... ...