NFIB rs28379954 does not affect CYP2D6-mediated metabolism of prototypical substrates, tamoxifen or solanidine
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Background: Cytochrome P450 2D6 (CYP2D6) is a highly polymorphic drug-metabolizing enzyme involved in the metabolism of many clinically important medications. CYP2D6 is affected by genetic variation as well as drug interactions; ... ...
