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Methotrexate use in juvenile idiopathic arthritis and its impact on growth plate development: A prospective observational cohort study

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Juvenile Idiopathic Arthritis (JIA) is a chronic inflammatory disease that can disrupt normal skeletal growth in children. Methotrexate (MTX) is widely used as a disease-modifying therapy in JIA, has uncertain effects on the developing growth plate and bone el... ...