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Efficacy of lidocaine-prilocaine combined with amitriptyline or Acmella oleracea in a liposomal cream for topical anesthesia: a randomized crossover clinical trial

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Background: Pain remains one of the main causes of apprehension during dental procedures. In this context, topical anesthetics play an essential role in reducing discomfort, and new compounds such as amitriptyline and jambu (Acme... ...