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Multi-pathway therapeutics in colorectal cancer: Targeting EMT, CSCs, and non-apoptotic cell death for drug resistance reversal

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Colorectal cancer (CRC) is a leading global malignancy, with therapeutic outcomes hampered by chemoresistance from epithelial-mesenchymal transition (EMT), colorectal cancer stem cells (CR-CSCs), and apoptosis evasion. Evidence highlights the therapeutic value... ...