Identification of novel PTP1B inhibitor for the treatment of LPS-induced myocardial apoptosis: machine learning based virtual screening and biological evaluation
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Sepsis-induced cardiovascular dysfunction (SICD) poses a serious threat to human life. Protein tyrosine phosphatase 1B (PTP1B) displays an essential role in SICD occurrence, so discovering novel inhibitors targeting PTP1B is an effective strategy for SICD trea... ...
