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CpG-induced immune responses via DNA micelles, gold nanoparticles, and liposomes

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CpG oligodeoxynucleotides (CpG ODNs) are well-known adjuvants that induce innate immunity, particularly dendritic cell activation, by stimulating Toll-like receptor 9. However, the stimulatory efficacy of CpG ODNs is limited by their negative charge, which cau... ...