A dysregulated hepcidin-iron axis impairs antiviral immunity and induces lethal liver pathology in neonates
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Systemic rotavirus (RV) infection poses a substantial health challenge in neonates, but the underlying pathogenesis remains elusive. In RV-infected neonatal mice and infants with biliary atresia (BA), we discovered that persistent type I interferon (IFN-I) sig... ...
