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Lung adenocarcinoma harboring uncommon EGFR exon 19 deletion L747_T751del and in cis K754E mutation: a case report and literature review

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E746_A750del, the most common and predominant EGFR exon 19 deletion in non-small cell lung cancer, shows excellent sensitivity to EGFR tyrosine kinase inhibitors. However, other uncommon EGFR exon 19 deletions show varying responses to EGFR-targeted inhibitors... ...