首页 正文

Integrin-dependence of extramedullary erythropoiesis in the spleen of Jak2-V617F positive myeloproliferative neoplasm in mice

{{output}}
The molecular mechanisms driving splenomegaly in myeloproliferative neoplasms (MPN) remain poorly understood. Utilizing the Jak2-V617F knock-in mouse model, we investigated the role of β1 and β2 integrins in regulating spleen volume and spleen weight. The re... ...