Catalytic Reductive Alkylation of Pyridine-Fused N-Heteroarenes Using Alkyl Formates as Transfer Hydroalkylation Reagents
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This work reports ruthenium-catalyzed tandem reductive alkylation of N-heteroarenes to form saturated azacycles. In this reaction, alkyl formates are used as a new class of hydroalkylation reagents with LiI as a promoter. The reaction proceeds via C-O σ-bond ... ...
