A chemical agonist and the Golgi-resident lipid PI4P activate STING by inducing transmembrane helix rearrangement
{{output}}
The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) signaling pathway is critical in innate immunity. Recent research has highlighted the importance of phosphatidylinositol 4-phosphate (PI4P) signaling within the Golgi apparatus for STING... ...
