PEGylated black-phosphorus nanosheet-alginate hydrogels enable local PRRX1 delivery to drive fibroblast reprogramming in intestinal fibrosis
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Intestinal fibrosis drives stricturing complications in Crohn's disease (CD), yet the core stromal regulators remain incompletely defined. Here, we profile paired fibrotic and non-fibrotic ileum from CD patients using single-cell RNA sequencing and identify a... ...