Chemo-, Regio- and Diastereoselective Synthesis of Azaspiro Tetra-/Pentacyclic Scaffolds with Anticancer Activity
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We report an efficient and highly selective synthesis of azaspiro polycyclic scaffolds with excellent chemo-, regio-, and diastereoselectivities. This method exhibits broad substrate scope (44 examples), and the resulting tetracyclic compounds can be readily e... ...