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A self-assembled nano micelle-exosome with high selectivity and penetrability achieves precise intracartilage lipid delivery

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To address the challenge of extremely low drug bioavailability in osteoarthritis (OA) cartilage, we developed a self-assembled micelle-exosome system (Mic-Exo) tailored to the specific characteristics of OA cartilage. The hydrophobic lipid layer of Mic-Exo ena... ...