Gene Cluster Directs Diversified Carbazole Biosynthesis via Cooperative Halogenation, Hydroxylation, and Methylation
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Chlocarbazomycins are bioactive carbazoles with therapeutic potential. Here, we report a conserved gene cluster (ccz) that directs its biosynthesis via a novel pathway. This cluster encodes a versatile tailoring system, including a regioselective halogenase (C... ...