Rebuilding the Marrow In Vitro: Translational Advances in the 3D Modeling of Blood Cancers
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Hematological malignancies such as acute myeloid leukemia (AML), chronic myeloid leukemia (CML), lymphomas, and multiple myeloma remain difficult to model ex vivo because conventional two-dimensional (2D) cultures and murine systems fail to reproduce the spati... ...