Discovery and Biosynthesis of Dehydroalanine-Containing Lasso Peptide by a Hybrid Biosynthetic System
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Lasso peptides and lanthipeptides are two major classes of ribosomally synthesized and post-translationally modified peptides (RiPPs), each defined by distinct post-translational modification (PTM) enzymes. We identify a hybrid biosynthetic gene cluster that i... ...
