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Guaiane-type sesquiterpenoids from patchouli oil and their potential anti-depressive effects

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Sixteen guaiane-type sesquiterpenoids, including four undescribed 4,5-seco-guaiane derivatives (1-4) and one undescribed guaiane (6), were isolated from the volatile oil of Pogostemon cablin. Their structures were determined using extensive spectroscopic evide... ...