A novel bispecific siRNA concept: Efficient dual knockdown of YAP1 and WWTR1 with a single guide strand
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Yes-associated protein (YAP, encoded by YAP1) and transcriptional coactivator with PDZ-binding motif (TAZ, encoded by WWTR1) are master transcriptional regulators in the Hippo pathway. Because of their complementary roles, simultaneously inhibiting these prote... ...
