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Cardiomyocyte Rac1 signaling in hypertrophy, arrhythmia, and cardiac stress adaptation

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Cardiovascular disease remains the leading cause of mortality globally and is often marked by pathologic cardiac remodeling including hypertrophy and fibrosis that promote the progression to heart failure. Ras-related C3 botulinum toxin substrate 1 (Rac1) is a... ...