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Lower total serum Immunoglobulin G is associated with impaired patient-reported health-related quality of life in systemic sclerosis: a prospective cross-sectional study

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Systemic sclerosis (SSc) is a connective tissue disease characterized by immune dysregulation, fibrosis, and vasculopathy, frequently resulting in substantial impairment in health-related quality of life (HRQoL). Total serum immunoglobulin G (IgG), a central c... ...