Copper-Iron-Catalyzed Cross-Coupling of ortho-Substituted Sulfonamides with Sterically Hindered (Hetero)aryl Chlorides and Alkyl Halides: Synthesis of Sulfonamide Drugs
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We describe for the first time an effective copper-iron-catalyzed cross-coupling strategy that enables the reaction for a diverse array of ortho-substituted primary (hetero)aryl and aliphatic sulfonamides with challenging sterically hindered (hetero)aryl chlor... ...