Pharmacological mechanisms and clinical applications between SGLT1 and SGLT2 inhibitors in type 2 diabetes and diabetic kidney disease: An analytic review
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Sodium-glucose cotransporters 1 and 2 (SGLT1 and SGLT2), key members of the solute carrier (SLC) family, are pivotal for glucose reabsorption. Inhibitors targeting these transporters act by competitively occupying the glucose-binding site, effectively blocking... ...