Transforming destructive mechanical cues into therapeutic power: Activation of PIEZO1 and TRPV4 counteracts mechano-induced damage of cellular junctions in Hailey-Hailey disease
{{output}}
Introduction: Hailey-Hailey disease (HHD) is characterized by impaired intracellular calcium transport due to ATP2C1 mutations, leading to defective interkeratinocyte adhesion and acantholysis, especially under mechanical stimula... ...
