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1,3-Dideazaguanosine in Atomic Mutagenesis Provides Unprecedented Insight Into Hydrogen Bonding and Stacking Interactions in Folded RNA

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The central goal of RNA atomic mutagenesis is to evaluate the presumed contacts between individual atoms and their interaction partners with regard to function. This is made possible, for instance, by deaza-modified nucleobases, which are introduced site-speci... ...