Exosomal LRG1 derived from highly metastatic non-small cell lung cancer cells accelerates growth, metastasis, and angiogenesis by transcriptional factor NFKB1-mediated SHH upregulation
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Neovascularization, a critical interstitial component, facilitates rapid tumor cell proliferation, metastasis, and recurrence. Communication between tumor-derived exosomes and endothelial cells promotes tumor progression and angiogenesis. Leucine-rich α2 glyc... ...