Endoplasmic Reticulum Stress Exacerbates Nucleus Pulposus Cell Pyroptosis via PERK-Dependent Activation of JAK1-STAT3 Signaling
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Endoplasmic reticulum stress (ERS) has been implicated in the pathophysiology of intervertebral disc degeneration (IDD), yet the precise molecular mechanisms linking excessive ERS to pyroptotic cell death in nucleus pulposus cells (NPCs) remain elusive. This s... ...
