CAFs-derived SPI1 in tumor fibroblasts promotes malignant behaviors of liver cancer cells and immune escape by regulating HRAS and PD-L1 transcription
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Background: As the fifth most common cancer worldwide, hepatocellular carcinoma (HCC) is a highly malignant disease with a formidable prognosis. Within the tumor microenvironment, cancer-associated fibroblasts (CAFs) play a param... ...