Mechanistic insights into 50 S precursor recognition and targeting by erythromycin resistance methyltransferase
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Erythromycin resistance methyltransferases (Erms) confer resistance to macrolide, lincosamide, and streptogramin B antibiotics by methylating an internal base (A2058, E. coli numbering) in an elusive precursor ribosomal state. Here, we capture the 50S ribosoma... ...
