A cell-autonomous role for the vitamin B6 metabolism gene PNPO in Drosophila GABAergic neurons
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In animals, the enzyme pyridox(am)ine 5'-phosphate oxidase (PNPO) is critical for synthesizing the active form of vitamin B6 (VB6), pyridoxal 5'-phosphate (PLP), from inactive vitamers. PLP is a required cofactor for many enzymatic reactions, including the s... ...
