Initiators counteract Polycomb repression and stimulate long-range contacts between enhancers and the Abdominal-B promoter in Drosophila
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The specification of abdominal segments A5 to A9 depends on the expression of Abdominal-B (Abd-B), which is regulated by four infraabdominal domains: iab-5 through iab-8,9. Each iab domain contains an initiation element that determines its active state, along ... ...
