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Systemic and skeletal muscle metabolic signatures associated with early insulin resistance in just-weaned non-obese Goto-Kakizaki diabetic rats

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The Goto-Kakizaki (GK) rat is a well-established experimental model for spontaneous non-obese type 2 diabetes mellitus (T2DM). However, the mechanisms underlying the early onset of the disease remain poorly understood. In this study, we investigated systemic a... ...