Exposure humidity and time control of lyophilization and enzyme engineering for stable isothermal nucleic acid detection reagents
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Isothermal nucleic-acid testing is ideal for on-site diagnostics, but large-scale lyophilization of reagents is hindered by three bottlenecks: costly in-situ capping of vials or PCR tubes, activity loss during non-in-situ transfer/sealing caused by ambient hum... ...