Zincke-Imine-Based Peripheral Editing of 2-Arylpyridines to Access 3-Acylpyridines
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Skeletal and peripheral editing of pyridines is a powerful strategy for the late-stage functionalization of N-heterocycles. While pyridines inherently exhibit high reactivity at the C2 and C4 positions, functionalization at the C3 position is significantly mor... ...