Loss of TET2 activity limits the ability of vitamin C to activate DNA demethylation in human HAP1 cells
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Background: The TET family of proteins-TET1, TET2, and TET3-are α-KG and Fe2+ dependent dioxygenases that play crucial roles in active DNA demethylation and the deposition of epigenetic marks such as 5-hydroxymethylcytosine, 5-f... ...
