Human plasma-derived eNAMPT-containing extracellular vesicles promote NAD+ biosynthesis and thermogenesis in mice
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Age-associated decline in tissue NAD+ levels contribute to functional impairments, recognized as aging. Nicotinamide phosphoribosyltransferase (NAMPT), the rate-limiting enzyme crucial for NAD+ biosynthesis in mammals, is encapsulated in extracellular vesicles... ...
