Potent Carbonic Anhydrase Inhibition by Ruthenium(II)-Acetazolamide Conjugates Uncoupled from Antiproliferative Activity In Vitro
{{output}}
The novel ruthenium(II) complexes [RuCl(κ3N-tpm)(PPh3)(κ1N-AcmH2)]Cl (5) and [Ru(κ3N-tpm)(PPh3)(κ2N,N'-AcmH)]NO3 (6) were synthesized in 46-57% yields via thermal reactions of [RuCl(κ3N-tpm)(PPh3)2]Cl (4) with AcmH2, conducted in THF and ethanol, respect... ...
