Mechanical stretch accelerates endothelial cell injury by inducing endoplasmic reticulum stress-mediated, autophagy-dependent ferroptosis in endothelial cells
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Portal hypertension is characterized by elevated pressure within the portal venous system, commonly resulting from cirrhosis. As portal hypertension progresses, the portal vein dilates and subjected its endothelial cells (ECs) to mechanical stretch. In this st... ...