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Evaluation of lapatinib ditosylate nanoparticles for enhanced dissolution rate, oral bioavailability and effective oral carcinoma treatment

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Lapatinib ditosylate (LD) is a chemotherapeutic agent that belongs to Class II of the Biopharmaceutical Classification System. The objective of this work was to enhance oral bioavailability of LD by developing a nanoparticle solid dispersion. Lapatinib ditosyl... ...