Size control of lipid nanoparticles via simulation-based design of a microfluidic chip and its effect on mRNA delivery in vitro and in vivo
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The emergence of mRNA-containing lipid nanoparticles (LNPs) during the COVID-19 pandemic has revolutionized vaccine technology and is now being explored for protein replacement therapies. This study aimed to test the hypothesis that LNP size, independent of li... ...