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Deficiency of SARM1 attenuates neuronal injury and improves neurological performance in a photothrombotic stroke model

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Stroke is a major cause of morbidity and mortality worldwide. There is an urgent need for effective neuroprotective agents to reduce brain injury. SARM1 (sterile alpha and TIR motif-containing 1) has been identified as a key mediator of axonal degeneration. Ho... ...