From stress to homeostasis: Mass spectrometry-based insights into the unfolded protein response (UPR) and proteostasis
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The unfolded protein response (UPR) is a central regulator of proteostasis, coordinating cellular adaptation to endoplasmic reticulum (ER) stress. It is comprised of three signaling branches: ATF6 (activating transcription factor 6), IRE1 (inositol-requiring e... ...
