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In vitro metabolic profiling of 6-chloro-testosterone and 6-ene-testosterone by liquid chromatography-mass spectrometry (LC-MS) and gas chromatography-time of flight (GC-TOF) mass spectrometry

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Among the phase-I reactions of 6-chloro-testosterone (6-CT), the reductive and oxidative dehalogenation, as well as the dehydrogenation, have been described here. One of the metabolic products could be the 6-ene-testosterone (6-ene-T). The goal of this work wa... ...