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Native Amide-Directed C(sp3)-H Alkynylation Using an Electron-Deficient Iridium Catalyst with Pyridone Ligand Assistance

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The direct functionalization of C(sp3)-H bonds assisted by native carbonyl functional groups is a promising strategy for the streamlined synthesis of complex molecules. Here, we report native amide-directed C(sp3)-H alkynylation reactions using an electron-def... ...