Synthesis of β-Amino-α-iminonitriles and α,β-Diiminonitriles Enabled by Lewis Acid-Catalyzed Double Isocyanide Insertion with Imines
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Lewis acid-catalyzed double isocyanide insertion with imines was disclosed for the efficient construction of synthetically useful functionalized iminonitriles in a chemoselective manner. Zn(OTf)2 catalyzed the synthesis of β-amino-α-iminonitriles from ketimi... ...