Organocatalytic Enantioselective Addition of 3-Aryloxindoles to Ethenesulfonyl Fluoride
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We report the synthesis of chiral sulfonyl fluorides bearing a carbon quaternary stereocenter. A commercially available organocatalyst (DHQD)2AQN enables the enantioselective addition of 3-substituted oxindoles to ethenesulfonyl fluoride (ESF), achieving excel... ...