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Multi-omics analysis of the HMGB2+ tumor epithelial cells in lactylation subgroups in colorectal cancer

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Colorectal cancer (CRC) is a prevalent malignancy, yet the role of lactylation in its progression remains unclear. This study investigates High Mobility Group Box 2 positive tumor epithelial cells (HMGB2+Epi), a lactylation-associated subpopulation. By integra... ...