Mechanistic basis for the opposing effects of H2A and H2B ubiquitination on nucleosome stability and dynamics
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Background: Nucleosome ubiquitination at lysine 119 of histone H2A (H2AK119ub) and lysine 120 of histone H2B (H2BK120ub) are prominent post-translational modifications with opposing roles in chromatin regulation. Although H2AK119... ...