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SENP3 Promotes Hepatocyte Steatosis via De-SUMOylation of SREBP2

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SENP3, a member of the sentrin-specific protease family, plays a pivotal role in lipid metabolism and the pathogenesis of fatty liver disease by regulating the dynamic process of SUMOylation. It has previously been demonstrated that SREBP2 is SUMOylated. Howev... ...